3D fibrin textiles for human implantations under development (16 - Nov - 2010)
Five Italian organizations are reportedly undertaking a research project to develop 3D fibrin textiles for optimizing the implantation of human pancreatic islands.

Called 'Panagenesi', the project aims to facilitate the root-taking process of transplanted islands - an issue to be dealt with at present - by developing fibrin variable circular section scaffolds for the purposes of reducing the number of pancreatic islands needed while prolonging their function over time.

Fibrin is reported to be a kind of highly biocompatible protein, which, extracted from silk, helps promote live tissue repairs while reducing inflammation. The fibrin variable circular section scaffold is a tubular textile article produced using fibrin yarns.

The organizations involved in the 'Panagenesi' project are Torcitura Di Menaggio, a silk yarn twisting company; Gaetano Rossini Holding, a 3D fabrics manufacturer; Comez, a narrow fabric technology machinery manufacturer; Stazione Sperimentale Per La Seta (Experimental Silk Center), a textile research center; and Milan's Niguarda Ca' Granda Hospital, a medical research center.

For the manufacturing of this tubular textile, Comez has designed an electronic double needle bed warp knitting machine. It can create spaced (3D) fabrics comprising two external fabrics forming the two faces of the fabric itself, combined by an internal structure. Its ability to distance the two needle beds allows for the gap between the two external fabrics to be increased or decreased. The variability of the circular section 3D tubular article is obtained by modifying the interlacing movement which constitutes the fabric's structure, varying the feeding of the yarns and number of stitches per centimeters. And the positive feeding of the threads allows for the processing of very fine yarns, such as fibrin, with very little resistance to mechanical action.

 

S.Nguyen (Source: Journal for Asia on Textile & Apparel)


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